Choose A Safe Vaccine
Respect natural mechanism & safety standards for maximal pandemic protection
Choose a safe vaccine to strengthen non-specific immunity for good personal protection against the pandemic
Optimize natural immune resources and deploy the body’s first line of defense
By Dr. Sun Ling Xian, a senior integrated Chinese and Western oncologist cum doctor of Chinese medicine (August 3, 2021)
In terms of vaccine production management and efficiency, DNA or mRNA nucleic acid vaccines show many advantages over traditional inactivated vaccines. For example, it is easier to control vaccine safety throughout the manufacturing process; and the antigen specificity enhances the neutralization potency of the antibody produced. It can also generate cellular immune responses. The application of genetic engineering to edit a single antigen message can be replicated in large quantities for easy, large-scale mass production. It can also be sequenced according to the genetic make-up of the latest virus variant, so that the next generation vaccine corresponding to the latest variant can be produced at any time. Collectively, the above factors can make this kind of vaccine continue to maintain the above-mentioned production advantages.
In particular, mRNA nucleic acid vaccines only need to go into the cytoplasm to encourage cells to produce viral antigens, unlike DNA nucleic acid vaccines which must enter the nucleus to be first transcribed into RNA, and then translated into antigens. For this reason, mRNA vaccines produce a lower genetic mutation risk compared to DNA vaccines. In view of the above advantages, the shortcoming of transporting and storing mRNA vaccines at very low temperature becomes acceptable.
But do the advantages of DNA or mRNA nucleic acid vaccines really outweigh their shortcomings? Except for traditional inactivated vaccines, almost all new vaccines developed around the world use [gene editing engineering] and [nano drug] technologies. Except for subunit protein vaccines such as Novavax as well as Taiwan's MVC vaccines and United Biomedical (UB-612) vaccines that do not produce antigens through the normal cells of the vaccinator, and [theoretically] may be safer than DNA and mRNA nucleic acid vaccines (refer Note), DNA adenovirus vaccines (such as AZ, Johnson & Johnson) or mRNA vaccines (such as Moderna, Pfizer BNT) require the vaccinator’s normal cells (such as muscle cells or vascular endothelial cells) to produce the viral spike protein as the antigen, which will in turn stimulate immune cells to produce specific antibodies to neutralize virus toxicity. This mechanism is more likely to cause a cellular immune response, instead of just antibody production, than a subunit protein vaccine. However, there exists a great disadvantage. This cellular immune response may also become the main cause of the endless side effects or complications after the nucleic acid vaccine injection?!
(Note: Subunit protein vaccines have been available for a shorter time and the number of people vaccinated is far less than that of other types of vaccines. Therefore, we can only use Novavax's clinical data and its theoretical mechanism of application to evaluate its relative safety profile in comparison to DNA or mRNA nucleic acid vaccines)
At present, both the adenovirus vector for DNA vaccine and the nanoparticle vector for mRNA vaccine are designed to penetrate the cell membrane of normal cells and enter the cell cytoplasm (or even the nucleus), which is equivalent to inserting a brand new ‘work instruction’ into our own normal cells. This new ‘work instruction’ orders normal cells to become factories for the production of viral spike proteins. The basic immunology principle tells us that if normal cells (such as capillary endothelial cells, cardiomyocytes) are told to produce antigens due to the action of DNA or mRNA vaccines, not only may it cause thrombosis, but it may also cause these cells to be attacked and killed by autoimmune cells.
Choosing a vaccine and medicine is contrary to the logic of choosing 3C electronic products. Medicines are like friends. The older the medicine, the safer it is. Choosing a safe vaccine is like subjecting the body to a ‘drill’ of viral attack. Even if you are infected with the latest virus variant in the future, your body will be able to produce the corresponding [specific antibodies] faster to mitigate symptoms and avoid mild to severe conditions as much as possible.
The mechanism of traditional Chinese medicine components of EX18 or TXL is different from that of vaccines that stimulate specific immune functions. EX18 or TXL uses a variety of polysaccharides and triterpenoids to activate the body's most important [non-specific] immune cells such as macrophages, CD4+, CD8+, CD16+56 and other T and NK cells, and strengthen functional immune cells of natural immunity to avoid wasting the body's limited immune resources. For example, after two or three doses of vaccines that give safety concerns, the immune cells are forced to make a pile of antibodies that are not necessarily able to directly neutralize the latest variant virus antigens. It is better to choose a safer vaccine, in conjunction with Chinese medicine, to regulate the immune function so as to optimize natural immune resources and deploy the body’s first line of defense. This practice will strengthen the body’s ability to suppress virus replication upon infection, and let the immune system gain some precious time to produce specific antibodies. This is a better epidemic prevention strategy that conforms to safety considerations.
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